Biretix
Acne-prone skin is one of the most commonly treated concerns at J Medical Aesthetics, and one of the most consistently complicated to manage at home. The gap between professional in-clinic treatment and what patients are using on their skin in between sessions makes a material difference to outcomes.
Biretix is the range we recommend for that gap.
Developed by Cantabria Labs (the global dermatology company behind Heliocare 360°), Biretix is a clinically proven, dermatologist-designed skincare collection built specifically for oily, congested, and acne-prone skin. It is not a general skincare range with an acne product or two appended to it. Every product in the Biretix collection is formulated to address a specific stage of the acne-prone skin cycle: purifying, treating, and supporting the skin’s barrier through the process.
At J Medical Aesthetics, we stock the full Biretix range as part of our commitment to supporting in-clinic results with the right home care, particularly for patients undergoing acne solutions treatment, chemical peel programmes, or managing post-inflammatory pigmentation and active congestion between appointments.
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What Makes Biretix Different
Most over-the-counter acne skincare addresses one part of the problem without considering the skin’s condition as a whole. Biretix takes a different approach, built on two proprietary technologies that work together to comprehensively and tolerably support acne-prone skin.
RetinSphere® Technology
Biretix’s most distinctive ingredient platform, RetinSphere® is a patented retinoid complex exclusive to Cantabria Labs. It combines two retinoid compounds: Hydroxypinacolone Retinoate (HPR) and Retinol encapsulated in microsponges, for both immediate and sustained release. This dual-delivery system provides the cell-renewal, pore-refining, and pigmentation-correcting benefits of retinoids while significantly reducing the irritation and dryness that commonly limit retinoid use in acne-prone skin.
RetinSphere® stimulates epidermal renewal, reduces blemishes and pore appearance, addresses post-acne marks and hyperpigmentation, and helps regulate skin cell turnover, making it an active ingredient rather than a supporting agent.
BIOPEP-15
A proprietary antimicrobial peptide technology that targets Cutibacterium acnes (the primary bacteria responsible for inflammatory acne) without disrupting the broader skin microbiome. BIOPEP-15 works to reduce bacterial proliferation and inflammation at the source, complementing the cell-renewal action of RetinSphere® with targeted antibacterial activity.
Together, these technologies are supported by clinically proven active ingredients, including glycolic acid for surface exfoliation, salicylic acid for pore decongestion, and niacinamide for barrier support, sebum regulation, and anti-inflammatory action.
The result is a range that is effective enough to produce measurable clinical improvement while being formulated to be tolerated by sensitive and sensitised skin.
The Biretix Range at J Medical Aesthetics
The Biretix collection follows three product pillars: purify, treat, and care – ensuring the range covers every stage of an acne-prone skincare routine rather than just targeting breakouts in isolation.
Biretix Cleanser
Available in 200mL and 400mL. A purifying cleansing gel formulated with BIOPEP-15, piroctone olamine (antibacterial and sebum-regulating), propolis extract, and aloe vera. Removes impurities, regulates excess oil, and reduces microbial proliferation without stripping or drying the skin. Physiological pH (5–6), non-comedogenic, and dermatologically tested. Suitable for daily use on combination, oily, and acne-prone skin.
Biretix Tri-Active Gel
A targeted treatment gel combining RetinSphere® and BIOPEP-15 with salicylic acid and niacinamide. Addresses active blemishes, enlarged pores, and blackheads while improving overall skin texture. The first-choice treatment product for patients with mild to moderate acne and visible pore congestion.
Biretix Tri-Active Spray
The same active formulation as the Tri-Active Gel in a spray format, designed for ease of application across larger or harder-to-reach areas such as the back and chest, which are common acne-prone zones that standard topical formats don’t address effectively.
Biretix Duo
A dual-action gel specifically formulated to address both blemishes and early fine lines. Combines RetinSphere® with targeted actives to treat active acne-prone skin while also addressing the textural and ageing concerns that become increasingly relevant in adult acne presentations. Particularly suited to patients in their late 20s and beyond, managing acne alongside early skin ageing.
Biretix Hydramat
A triple-effect moisturiser designed for oily and acne-prone skin that provides up to 72 hours of hydration while simultaneously regulating oil production, mattifying the skin, and preventing the formation of post-inflammatory hyperpigmentation (PIH). Non-comedogenic. The daily moisturiser of choice for patients whose skin is actively congested or oily.
Biretix Isorepair
An intensive hydrating recovery cream formulated for skin sensitised by treatment, including oral or topical retinoid therapy, professional chemical peels, and other active skin treatments. Contains barrier repair technology, hyaluronic acid, and soothing agents to restore skin barrier function, reduce tightness and irritation, and support skin recovery without blocking pores. A key product for patients undergoing active treatment programmes.
Biretix Mask
A purifying treatment mask for use 1–2 times weekly. Helps decongest pores, reduce sebum, and clarify the skin between daily product applications. A useful addition for patients with persistently congested or oily skin seeking deeper weekly treatment support.
Biretix Micropeel
A gentle exfoliating treatment with a combination of AHAs and BHAs. Addresses surface texture, dullness, and mild post-inflammatory marks. Suitable for use between professional chemical peel treatments to maintain the exfoliation and renewal process at home.
Who Biretix is For
Biretix is formulated for adults with oily, combination, and acne-prone skin, particularly those dealing with mild to moderate acne, persistent congestion, post-blemish marks, enlarged pores, or skin sensitised by active treatment.
It is equally well-suited as a standalone daily skincare regime for patients managing acne at home, and as a maintenance and support programme for patients undergoing in-clinic acne treatment, professional peels, or other active skin therapies. The Isorepair and Hydramat products in particular are frequently recommended at J Medical Aesthetics as part of post-treatment aftercare protocols.
For patients working through a broader skin concern programme, such as those also addressing acne solutions in-clinic, or managing pigmentation alongside congestion, Biretix integrates cleanly with professional treatment plans without interfering with other actives.
Biretix Alongside Other Skincare Ranges
At J Medical Aesthetics, Biretix sits within a broader portfolio of clinical skincare brands, each selected for specific skin presentations and goals.
For patients whose primary concerns extend beyond acne to address pigmentation, ageing, or general skin health, the Dermaceutic skincare range offers complementary options with a focus on correction and rejuvenation. For patients interested in a broader skin health approach, the ISDINceutics range provides clinically formulated options across a range of concerns.
Your practitioner will advise on the most appropriate products and combination at consultation, ensuring home care works with your in-clinic treatment plan.
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Related Treatments
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Isdinceutics Range
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FAQs
Frequently Asked Questions
Still have a question about your treatment? Speak with our team before you book.
What is Biretix, and who makes it?
Biretix is a clinically proven skincare range developed by Cantabria Labs, a global dermatology company known for research-led formulations. It is designed specifically for oily, congested, and acne-prone skin, and is built around two proprietary technologies: RetinSphere® (a patented dual-retinoid complex) and BIOPEP-15 (an antimicrobial peptide). Every product in the Biretix range is formulated to address a specific stage of the acne-prone skin cycle.
Is Biretix suitable for sensitive skin?
Yes. Despite containing active ingredients including retinoids, salicylic acid, and glycolic acid, the Biretix formulations are developed with tolerability as a core consideration. RetinSphere® delivers retinoid benefits with significantly reduced irritation compared to standard retinol, and the Isorepair product is specifically designed for skin sensitised by treatment. That said, as with any active skincare, introducing products gradually and following professional guidance is recommended.
Can Biretix be used alongside professional skin treatments?
Yes, and this is one of its most relevant applications. Biretix integrates well alongside professional acne solutions treatment, chemical peel programmes, and other in-clinic therapies. The Isorepair cream, in particular, is designed to support skin recovery after active treatments. Your practitioner will advise on which Biretix products are appropriate at each stage of your treatment plan.
How long does it take to see results with Biretix?
Clinical studies using RetinSphere® and BIOPEP-15 together showed measurable improvement in acne-prone skin from 14 days, with continued improvement over 42 days of consistent use. As with all active skincare, consistent daily use is required to achieve and sustain results. Biretix is designed for ongoing use rather than short-term correction.
Which Biretix product should I start with?
The right starting point depends on your skin type, concerns, and whether you are currently undergoing any professional treatments. As a general guide: the Cleanser is suitable for most acne-prone skin types as a daily foundation; the Tri-Active Gel is the primary treatment product for active congestion and blemishes; and the Hydramat is the moisturiser of choice for oily and combination skin. A consultation at J Medical Aesthetics will help identify the right combination for your specific skin.
How does Biretix differ from other skincare ranges stocked at J Medical Aesthetics?
Biretix is the only range in our portfolio formulated exclusively for acne-prone and oily skin, with every product designed around the acne skin cycle. Other ranges, such as Dermaceutic and ISDINceutics, address broader skin concerns, including pigmentation, ageing, and general skin health. Your practitioner will recommend the most appropriate range, or combination of ranges, based on your individual skin assessment.








